Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes that results from the impaired killing of fungi and bacteria, which can lead to severe, recurrent, and life-threatening infections.1

1. Leiding JW, Holland SM. Chronic granulomatous disease. In: Pagon RA, Adam MP, Ardinger HH, et al, eds. GeneReviews®. Seattle, WA: University of Washington, Seattle; 1993-2018.