With a simple blood draw, the dihydrorhodamine (DHR) test can determine if a person has chronic granulomatous disease (CGD) or is a carrier of CGD.

Transcript

Dihydrorhodamine (DHR) Collection Kit directions.

The dihydrorhodamine or DHR test is a blood test used to test for chronic granulomatous disease (CGD). It can also detect the type of CGD or carrier status.

The DHR Collection Kit is used to collect and ship blood samples to be tested for CGD using the DHR test.

In this video, we will go over the correct way for the HCP, patient, and lab staff who draw the blood to use the kit. This will help ensure the samples are processed and tested properly.

DHR Collection Kit directions for healthcare professionals (HCPs).

Before the kit can be used, the HCP must complete the ARUP requisition form and include the completed form with the kit to ensure that the test is processed correctly. Incomplete forms may prevent test processing.

This DHR test is valid for CGD testing only.

HCPs will determine if their office is equipped to perform the blood draw. If not, Horizon Therapeutics has partnered with Quest Diagnostics Patient Service Centers where the patient and donor will need to go to for the blood draw. Check the INSTRUCTIONS FOR USING YOUR DHR COLLECTION KIT card to make sure the correct forms are completed based on where the blood draw will be performed. HCPs should also review the patient instructions included in the kit with the patient or caregiver before the blood draw appointment.

Inform patients or caregivers that they need to bring a nonrelated, healthy donor with them for the blood draw.

If the blood draws will not be performed in the HCP's office, details on how to make an appointment and locate the nearest Quest Diagnostics Patient Service Center are included in the patient instructions.

If the blood draw is performed in the HCP’s office, office staff MUST immediately call FedEx to arrange for same-day pickup to ensure neutrophils are processed within 24 to 36 hours.

Whether the patient is going to a Patient Service Center or Quest Diagnostics for the blood draw, in addition to the ARUP Laboratory Requisition Form, the HCP also needs to fill out the Quest Diagnostics Lab Order Form provided in the kit.

Both forms must be completed in full and match.

Then give the DHR Collection Kit to the patient. The patient must bring the entire kit—including the 2 completed forms from their HCP’s office—with them for the blood draw.

Once the samples from the DHR Collection Kit have been received and processed, results will be sent to the ordering HCP via fax from ARUP Laboratories within 2 to 3 days.

The ordering HCP can request an enhanced report, including a histogram, by calling ARUP Client Services at 1-800-522-2787 and providing the Horizon Client ID, which is 282419.

If you have any questions, review the checklist below this video.

CGD Pathways is proud to offer the DHR Collection Kit free of charge.

HEALTHCARE PROFESSIONALS: Tips for the proper use of the DHR Collection Kit

DHR Collection Kits are sent directly to healthcare professionals, who either perform the blood draw in their offices or send the collection kit to a laboratory. Because the testing process has some very specific steps, it’s important that healthcare professionals, patients, and lab staff know how to use the collection kit properly.

Step 1 - complete the ARUP requisition form

Complete the ARUP requisition form before patients get their blood drawn to ensure that the kit is processed correctly. If the blood draw is occurring at a Quest Diagnostics Patient Service Center, fill out the Quest coupon in order for the test to be performed at no cost.

Step 2 - review the patient instructions

Review the patient instructions included in the kit with patients.

Step 3 - give the entire DHR Collection Kit and paperwork to patients

Give the entire DHR Collection Kit and associated paperwork to patients to take to their appointment.

Note: Testing for CGD while the patient has an active infection is not recommended.

COMMUNICATION OF RESULTS

Results will be provided and an enhanced report and histogram will be accessible.

For questions about results, contact ARUP Client Services at 1 (800) 522-2787. Mention client ID 282419 and Horizon.

  • ARUP is available 24 hours a day, 365 days a year
  • Visit www.aruplab.com
  • Test code: 0096657 (neutrophil oxidative burst assay)
  • CPT code: 82657

Order a DHR test for CGD at no cost

Request a Kit

Transcript

DHR Collection Kit directions for patients.

The DHR test requires that 2 vials of blood are collected at the same time: 1 from the person getting tested and 1 from an unrelated, healthy donor.

Once the donor is identified, an appointment needs to be scheduled to have blood drawn at the same time at either the healthcare professional’s office or nearest Quest Diagnostics Patient Service Center.

The appointment should be scheduled between Monday and Thursday before 1 PM so that samples can be processed appropriately.

Do not schedule appointments on a Friday, over the weekend, or the day before a holiday. If the HCP suggests getting blood drawn at a center, there is a Quest Diagnostics Lab Order Form in the DHR Collection Kit that should be given to the lab staff at the appointment. Along with the ARUP Laboratory Requisition Form, this form MUST be filled out by the HCP before the blood draw appointment. The information should match on both forms.

The entire DHR Collection Kit—including the forms completed by the HCP’s office—must be taken to the blood draw appointment.

The DHR test will be processed, and the HCP will share the results only with the person being tested in 1 to 2 weeks. The control donor will not see the results.

If you have any questions, review the checklist below this video.

CGD Pathways is proud to offer the DHR Collection Kit free of charge.

PATIENTS: Tips for the proper use of the DHR Collection Kit

DHR Collection Kits are sent directly to healthcare professionals, who either perform the blood draw in their offices or send the collection kit to a laboratory. Because the testing process has some very specific steps, it’s important that healthcare professionals, patients, and lab staff know how to use the collection kit properly.

Step 1 - find a healthy, nonrelated control donor

Find a healthy, nonrelated control donor to take the test at the same time as you or your child.

  • Two samples of blood must be collected: 1 from the patient and 1 from the donor
  • If a patient needs to go to a Quest Diagnostics Patient Service Center for their blood draw, they should schedule 1 appointment for both blood draws
Step 2 - schedule blood draw

Schedule blood draw for Monday through Thursday before 2 PM so the blood sample can be shipped the same day.

  • Blood-draw appointments should not be scheduled on Fridays, weekends, the day before a holiday, or late in the afternoon
Step 3 - patients should bring entire DHR Collection Kit to their blood draw

Patients should bring the entire DHR Collection Kit to their blood draw, including the:

  • Completed requisition form (“ARUP Only” envelope)
  • “Patient Instructions” envelope
  • Quest envelope for the lab staff if a Quest Diagnostics Patient Service Center is being used

Patients with questions about the test or test results should contact their healthcare professionals.

Transcript

DHR Collection Kit directions for lab staff.

Check the INSTRUCTIONS FOR USING YOUR DHR COLLECTION KIT to see the 2 forms that must be completed if the blood draw is performed in the healthcare professional’s office or at a Quest Diagnostics Patient Service Center.

The DHR Collection Kit includes instructions that explain how to use the supplies inside to properly prepare the 2 specimens, package them, and ship them for processing.

For the DHR test, it is vital to clearly identify who is the patient and who is the control donor.

Lab staff should draw at least 3 to 5 milliliters of venous whole blood into one of the vials provided, then fill out the Patient Specimen vial label and affix it immediately after.

Next, draw at least 3 to 5 milliliters of venous whole blood from the healthy, nonrelated donor as a control sample. Then fill out the Control Specimen vial label and affix it immediately after.

Place both vials into the absorbent sleeve provided.

Blood samples are temperature sensitive, as live neutrophils are required, and should be kept at room temperature. The specimens should NOT be refrigerated, frozen, spun in a centrifuge, or shaken.

Place the absorbent sheet containing the vials into the styrofoam mailer. Then place the styrofoam mailer into the 95kPa bag then seal the bag.

Make sure the referring HCP has filled out the ARUP Laboratory Requisition Form.

The date and time of blood draw must be entered on the ARUP Laboratory Requisition form by the ordering physician.

Place all completed forms and the blood sample mailer into the provided FedEx® envelope.

Call FedEx immediately to schedule a same-day pickup. The kit must be shipped the same day as the blood draw to ensure neutrophils are processed within 24 to 36 hours.

If you have any questions, review the checklist below this video.

CGD Pathways is proud to offer the DHR Collection Kit free of charge.

LAB STAFF: Tips for the proper use of the DHR Collection Kit

DHR Collection Kits are sent directly to healthcare professionals, who either perform the blood draw in their offices or send the collection kit to a laboratory. Because the testing process has some very specific steps, it’s important that healthcare professionals, patients, and lab staff know how to use the collection kit properly.

Step 1 - Do not freeze, refrigerate, add coolant, shake, or spin blood samples in a centrifuge

Do NOT do any of the following to blood samples: refrigerate, freeze, add coolant, spin in a centrifuge, or shake.

Step 2 - DHR Collection Kit must be shipped the same day blood is drawn

Lab staff MUST ship the DHR Collection Kit the same day that blood is drawn. Overnight shipping should be used to ensure that blood samples arrive for analysis the day after the blood is drawn. A prepaid FedEx® label is included in the kit and lab staff must call FedEx to ensure same-day pickup of the completed kit.

Lab staff with questions about specimen processing should call ARUP at 1 (800) 522-2787. Please provide client ID 282419 and mention Horizon when calling.